Article
Molecular-neurobehavioral associations in females with the fragile X full mutation.
American journal of medical genetics - 15 Jul 1994
Abrams M T, Reiss A L, Freund L S, Baumgardner T L, Chase G A, Denckla M B
Abstract excerpt
In this study, young females with the fragile X [fra(X)] full mutation (fM) were assessed using quantitative measures of mutation amplification size (Amp) as well as the ratio of active normal X chromosome to total normal X chromosome (activation ratio-AR). Neurobehavioral assessments of females...
Topics
- Adolescent
- Adult
- Child
- Child, Preschool
- DNA
- Dinucleoside Phosphates
- Dosage Compensation, Genetic
- Female
- Fragile X Syndrome
- Gene Dosage
- Heterozygote
- Humans
- Intelligence
- Intelligence Tests
- Mental Disorders
- Methylation
- Mutation
- Neuropsychological Tests