Superoxide dismutase concentration and activity in familial amyotrophic lateral sclerosis.

doi:10.1046/j.1471-4159.1995.64052366.x

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Article

Superoxide dismutase concentration and activity in familial amyotrophic lateral sclerosis.

Journal of neurochemistry - 1 May 1995

Bowling A C, Barkowski E E, McKenna-Yasek D, Sapp P, Horvitz H R, Beal M F, Brown R H

Abstract excerpt

Some cases of autosomal-dominant familial amyotrophic lateral sclerosis (FALS) have been associated with mutations in SOD1, the gene that encodes Cu/Zn superoxide dismutase (Cu/Zn SOD). We determined the concentrations (microgram of Cu/Zn SOD/mg of total protein), specific activities (U/microgram...

Topics

Adult
Aged
Amyotrophic Lateral Sclerosis
Erythrocytes
Female
Humans
Male
Middle Aged
Mutation
Regression Analysis
Superoxide Dismutase

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