Article
Superoxide dismutase concentration and activity in familial amyotrophic lateral sclerosis.
Journal of neurochemistry - 1 May 1995
Bowling A C, Barkowski E E, McKenna-Yasek D, Sapp P, Horvitz H R, Beal M F, Brown R H
Abstract excerpt
Some cases of autosomal-dominant familial amyotrophic lateral sclerosis (FALS) have been associated with mutations in SOD1, the gene that encodes Cu/Zn superoxide dismutase (Cu/Zn SOD). We determined the concentrations (microgram of Cu/Zn SOD/mg of total protein), specific activities (U/microgram of total protein), and apparent turnover numbers (U/mumol of Cu/Zn SOD) of Cu/Zn SOD in erythrocyte lysates from...
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