Article
Phenotypic expression and frequency of familial defective apolipoprotein B-100 in Belgian hypercholesterolemics.
Atherosclerosis - 1 Dec 1994
Kotze M J, Peeters A V, Langenhoven E, Wauters J G, Van Gaal L F
Abstract excerpt
DNA screening for apolipoprotein (apo) B mutations causing familial defective apolipoprotein B-100 (FDB) was performed in 87 hyperlipidemic Belgian individuals using heteroduplex analysis. Eighteen FDB heterozygotes from 5 unrelated families were identified. Three of the index cases reported an e...
Topics
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Apolipoprotein B-100
- Apolipoproteins B
- Base Sequence
- Belgium
- Child
- Child, Preschool
- Female
- Gene Expression
- Heterozygote
- Humans
- Hyperlipoproteinemia Type II
- Male
- Middle Aged
- Molecular Sequence Data