Analysis of a Hind III site polymorphism in the type II collagen gene: it's location and frequencies in the Japanese population.

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Analysis of a Hind III site polymorphism in the type II collagen gene: it's location and frequencies in the Japanese population.

Nihon Seikeigeka Gakkai zasshi - 1 Jan 1995

Nakamura M, Nakamura M, Okazaki K, Masumi S

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Hind III restriction fragment length polymorphism (RFLP) in the cartilage-specific type II collagen gene was studied in a sample of 135 persons randomly selected from the Japanese population. Localization of the Hind III site was determined by the dideoxy method. Based on this sequence, a pair of primers was designed and a polymerase chain reaction (PCR) was carried out. The Hind III allele had a frequency of...

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Analysis of a Hind III site polymorphism in the type II collagen gene: it's location and frequencies in the Japanese population.

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