Article
Analysis of a Hind III site polymorphism in the type II collagen gene: it's location and frequencies in the Japanese population.
Nihon Seikeigeka Gakkai zasshi - 1 Jan 1995
Nakamura M, Nakamura M, Okazaki K, Masumi S
Abstract excerpt
Hind III restriction fragment length polymorphism (RFLP) in the cartilage-specific type II collagen gene was studied in a sample of 135 persons randomly selected from the Japanese population. Localization of the Hind III site was determined by the dideoxy method. Based on this sequence, a pair of primers was designed and a polymerase chain reaction (PCR) was carried out. The Hind III allele had a frequency of...
Topics
- Asian People
- Base Sequence
- Cartilage
- Collagen
- Deoxyribonuclease HindIII
- Gene Frequency
- Genotype
- Humans
- Japan
- Molecular Sequence Data
- Polymerase Chain Reaction