Article
HindIII(+/-) polymorphism of the Y chromosome, blood pressure, and serum lipids: no evidence of association in three white populations.
American journal of hypertension - 1 Apr 2006
Russo Paola, Venezia Antonella, Lauria Fabio, Strazzullo Pasquale, Cappuccio Francesco P, Iacoviello Licia, Barba Gianvincenzo, Siani Alfonso
Abstract excerpt
BACKGROUND: Male sex is associated with elevated levels of cardiovascular risk factors, including higher blood pressure (BP). Genetic variants on the Y chromosome may contribute to explain the sexual dimorphism in cardiovascular diseases. Among them, the HindIII(+/-) polymorphism of the male-specific region of the Y chromosome has been associated with BP and serum cholesterol levels, with conflicting results. We...
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