Article
PCR amplification of rRNA intergenic spacer regions as a method for epidemiologic typing of Clostridium difficile
1 Jan 1995
Abstract excerpt
From January to March 1993, a suspected outbreak of antibiotic-associated diarrhea occurred on a pediatric oncology ward of the Clinical Center Hospital at the National Institutes of Health. Isolates of Clostridium difficile obtained from six patients implicated in this outbreak were typed by both PCR amplification of rRNA intergenic spacer regions (PCR ribotyping) and restriction endonuclease analysis of genomic...
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