Golgi and vacuolar membrane proteins reach the vacuole in vps1 mutant yeast cells via the plasma membrane.

doi:10.1083/jcb.129.1.35

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Article

Golgi and vacuolar membrane proteins reach the vacuole in vps1 mutant yeast cells via the plasma membrane.

The Journal of cell biology - 1 Apr 1995

Nothwehr S F, Conibear E, Stevens T H

Abstract excerpt

The Vps1 protein of Saccharomyces cerevisiae is an 80-kD GTPase associated with the Golgi apparatus. Vps1p appears to play a direct role in the retention of late Golgi membrane proteins, which are mislocalized to the vacuolar membrane in its absence. The pathway by which late Golgi and vacuolar membrane proteins reach the vacuole in vps1 delta mutants was investigated by analyzing transport of these proteins in...

Topics

Amino Acid Sequence
Carrier Proteins
Cell Membrane
GTP-Binding Proteins
Genotype
Golgi Apparatus
Intracellular Membranes
Membrane Proteins
Models, Biological
Molecular Sequence Data
Mutagenesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Open Reading Frames

Proprotein Convertases

Saccharomyces cerevisiae

Saccharomyces cerevisiae Proteins

Subtilisins

Temperature

Vacuoles

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Identifiers

PMID: 7698993
DOI: 10.1083/jcb.129.1.35
PMCID: PMC2120360

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7698993-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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