Article
Comparison between immunogenotypic findings in de novo AML and AML post MDS.
Leukemia - 1 Nov 1993
Ohyashiki J H, Ohyashiki K, Kawakubo K, Fujimura T, Shimamoto T, Nakazawa S, Kimura N, Toyama K
Abstract excerpt
We compared immunogenotypic findings in 73 patients with de novo acute myeloid leukemia (AML) and 30 patients with AML developed in myelodysplastic syndrome (AML post MDS) to determine the biological difference between these hematopoietic neoplasias. Lymphoid-associated antigens were detected in 13 patients with de novo AML, four of whom exhibited rearrangement of the immunoglobulin heavy-chain (IgH) gene. T-cell...
Topics
- Adult
- Aged
- Aged, 80 and over
- Antigens, CD
- Antigens, CD19
- Antigens, CD7
- Antigens, Differentiation, B-Lymphocyte
- Antigens, Differentiation, T-Lymphocyte
- Blotting, Southern
- Female
- Gene Rearrangement, B-Lymphocyte, Heavy Chain
