Article
Molecular basis for human immunodeficiencies.
Current opinion in immunology - 1 Aug 1993
Hammarström L, Gillner M, Smith C I
Abstract excerpt
Major emphasis is currently being placed on unraveling the molecular basis of various forms of primary human immunodeficiencies. It is clear from recent studies that not only can different mutations give rise to different phenotypes but the same mutation may result in quite diverse clinical pictures. A correct diagnosis at the DNA level therefore becomes increasingly important in view of the possibility of gene...
Topics
- Agammaglobulinemia
- Antigens, CD
- Antigens, Differentiation, B-Lymphocyte
- CD40 Antigens
- Common Variable Immunodeficiency
- Complement System Proteins
- Genetic Linkage
- Humans
- Hypergammaglobulinemia
- IgA Deficiency
- Immunoglobulin M