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Cystic fibrosis: influence of CFTR variants on epididymal sperm recovery and ICSI results

8 May 2025

Abstract excerpt

RESEARCH QUESTION: How do microsurgical epididymal sperm aspiration (MESA) outcomes in men with cystic fibrosis compare with those with cystic fibrosis transmembrane conductance regulator (CFTR)-related disorders (CFTR-RD), and what is the impact of CFTR variants on MESA success rates and subsequent cumulative outcomes after ICSI? DESIGN: A retrospective cohort study, conducted from 2003 to 2023 at Lille...

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PMID: 40850271
DOI: 10.1016/j.rbmo.2025.105042

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