Article
Keratin diseases.
Current opinion in genetics & development - 1 Jun 1994
Lane E B
Abstract excerpt
The recent discovery that epidermal fragility syndromes can be caused by mutations in the genes for keratin intermediate filaments has been a turning point for research into these structural proteins. Clustering of pathogenic mutations implies differential structural sensitivity along the keratin...
Topics
- Amino Acid Sequence
- Humans
- Keratins
- Models, Biological
- Molecular Structure
- Mutation
- Phenotype
- Skin Diseases