Article
Phenotype changes in tumor vessels associated with the progression of hepatocellular carcinoma.
Japanese journal of clinical oncology - 1 Apr 1993
Sakamoto M, Ino Y, Fujii T, Hirohashi S
Abstract excerpt
Human hepatocellular carcinoma (HCC) is characterized by hypervascularity and tumor staining in angiograms, and tumor angiogenesis is considered indispensable for tumor growth. HCC is also characterized by an obvious multistage process of tumor progression. To find out in which stage of human hepatocarcinogenesis angiogenesis occurs, we have carried out a pathological study, of the phenotypic changes in tumor...
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