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Article

Allelic variations of human keratins K4 and K5 provide polymorphic markers within the type II keratin gene cluster on chromosome 12.

The Journal of investigative dermatology - 1 Jun 1993

Wanner R, Förster H H, Tilmans I, Mischke D

Abstract excerpt

To appreciate point mutations in keratin genes as causes for hereditary epithelial diseases, the normal variation of these gene sequences in the population must be known. Because genetic polymorphism of keratins at the protein level due to allelic variation has been described for the type II kera...

Topics

Alleles
Amino Acid Sequence
Base Sequence
Chromosomes, Human, Pair 12
Gene Amplification
Gene Frequency
Humans
Keratins
Molecular Sequence Data
Multigene Family
Pedigree
Polymorphism, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 7684424
DOI: 10.1111/1523-1747.ep12475671

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7684424-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Allelic variations of human keratins K4 and K5 provide polymorphic markers within the type II keratin gene cluster on chromosome 12.PMID 7684424Read ↗

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