Mutations in the genes for epidermal keratins in epidermolysis bullosa and epidermolytic hyperkeratosis.

Article

Mutations in the genes for epidermal keratins in epidermolysis bullosa and epidermolytic hyperkeratosis.

Archives of dermatology - 1 Dec 1993

Leigh I M, Lane E B

Abstract excerpt

BACKGROUND: Clues from clinicopathologic studies of epidermolysis bullosa simplex (EBS) and epidermolytic hyperkeratosis (EH) have implicated abnormalities in keratin filaments as possibly underlying the pathogenesis of these diseases. Multiple avenues of study have now converged, which confirm t...

Topics

Epidermis
Epidermolysis Bullosa
Genes
Humans
Hyperkeratosis, Epidermolytic
Keratins
Mutation

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