Article
The significance of DNA double-strand breaks in the UV inactivation of yeast cells.
Mutation research - 1 May 1993
Kiefer J, Feige M
Abstract excerpt
The radiation-sensitive mutant rad 54-3 of Saccharomyces cerevisiae temperature-conditional for the repair of DNA double-strand breaks was exposed to 254 nm ultraviolet radiation and incubated at the restrictive and permissive temperatures. A large difference in survival was seen indicating the involvement of double-strand breaks in cellular inactivation at least in this strain. Pulsed-field gel electrophoresis...
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