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Article

Expression of the cystic fibrosis transmembrane conductance regulator from a novel adeno-associated virus promoter.

1 Feb 1993

Abstract excerpt

Adeno-associated virus type 2 (AAV) vectors have been used for gene expression in respiratory epithelial cells and may be useful in gene therapy for diseases like cystic fibrosis (CF) which affect the airways. The AAV p5 promoter together with the AAV inverted terminal repeat (ITR) forms a 263-base pair cassette which mediated efficient expression in a CF bronchial epithelial cell line. We report here that the...

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Identifiers

PMID: 7679117
DOI: 10.1016/s0021-9258(18)53762-5

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