Genetic and clinical features of 42 kindreds with resistance to thyroid hormone. The National Institutes of Health Prospective Study.

doi:10.7326/0003-4819-123-8-199510150-00002

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Article

Genetic and clinical features of 42 kindreds with resistance to thyroid hormone. The National Institutes of Health Prospective Study.

Annals of internal medicine - 15 Oct 1995

Brucker-Davis F, Skarulis M C, Grace M B, Benichou J, Hauser P, Wiggs E, Weintraub B D

Abstract excerpt

OBJECTIVE: To determine the genetic and clinical features of resistance to thyroid hormone in a study from a single institution. DESIGN: Prospective, controlled study. SETTING: National Institutes of Health. PATIENTS: 104 patients with resistance to thyroid hormone from 42 kindreds and 114 unaffected relatives sharing the patients' environmental and genetic backgrounds. MEASUREMENTS: Thyroid, cardiovascular,...

Topics

Adolescent
Adult
Aged
Attention Deficit Disorder with Hyperactivity
Body Height
Child
Child, Preschool
Drug Resistance
Female
Genes, Dominant
Goiter

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Infant

Intelligence

Male

Middle Aged

Mutation

Pedigree

Source

Open in PubMed

Identifiers

PMID: 7677297
DOI: 10.7326/0003-4819-123-8-199510150-00002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7677297-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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