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Article

Molecular biology of gastric cancer.

World journal of surgery - 1 Jan 2000

Tahara E

Abstract excerpt

Gastric cancer involves changes in multiple oncogenes and multiple suppressor genes, and it causes genetic instability. Aberrant expression and amplification of the c-met gene, inactivation of the p53 gene, and CD44 abnormal transcripts are common events of both well differentiated and poorly differentiated gastric cancers. Amplification of the cyclin E gene is also observed in gastric cancer regardless of...

Topics

Adenocarcinoma
Cell Adhesion Molecules
Cytokines
Genes, p53
Growth Substances
Humans
Mutation
Proto-Oncogenes
Receptor Protein-Tyrosine Kinases
Stomach Neoplasms

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 7676688
DOI: 10.1007/BF00294705

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APC
DCC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7676688-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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