Article
Molecular biology of gastric cancer.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico - 1 Apr 2007
Cervantes A, Rodríguez Braun E, Pérez Fidalgo A, Chirivella González I
Abstract excerpt
Despite its decreasing incidence overall, gastric cancer is still a challenging disease. Therapy is based mainly upon surgical resection when the tumour remains localised in the stomach. Conventional chemotherapy may play a role in treating micrometastatic disease and is effective as palliative therapy for recurrent or advanced disease. However, the knowledge of molecular pathways implicated in gastric cancer...
Topics
- Adult
- Aged
- Biomarkers, Tumor
- Cell Adhesion
- Gastrectomy
- Genes, Tumor Suppressor
- Genetic Markers
- Humans
- Male
- Microsatellite Instability
- Mutation
- Neovascularization, Pathologic
- Prognosis
- Protein-Tyrosine Kinases
- Proto-Oncogenes
- Signal Transduction
- Stomach
- Stomach Neoplasms
