Article
Physical map of the region containing the gene for Batten disease (CLN3).
American journal of medical genetics - 5 Jun 1995
Järvelä I E, Mitchison H M, Callen D F, Lerner T J, Doggett N A, Taschner P E, Gardiner R M, Mole S E
Abstract excerpt
CLN3 has been mapped genetically to 16p12, to the interval between D16S288 and D16S383, a sex-averaged genetic distance of 2.1 cM. Analysis of disease haplotypes for four microsatellite markers in this interval, D16S288, D16S299, D16S298, and SPN, has shown significant allelic association between...
Topics
- Alleles
- Chromosome Mapping
- Chromosomes, Artificial, Yeast
- Chromosomes, Human, Pair 16
- DNA, Satellite
- Female
- Haplotypes
- Humans
- Male
- Neuronal Ceroid-Lipofuscinoses
- Repetitive Sequences, Nucleic Acid