Article
Characteristics of spontaneous revertants in haploid yeast.
Yeast (Chichester, England) - 30 Jun 1995
Korogodina V L, Korogodin V I, Simonyan N V, Maiorova E S
Abstract excerpt
The appearance dynamics of spontaneous revertants in adenine- or leucine-auxotrophic haploid Saccharomyces cerevisiae strains has been studied using mathematical simulation methods. In the case of adenine auxotrophs an increase in the number of revertants with decreasing metabolite content is found to result mainly from increasing the rate of intragenic suppressor mutations. In the case of leucine auxotrophs...
Topics
- Culture Media
- Haploidy
- Leucine
- Mutation
- Saccharomyces cerevisiae
