Article
Clinical and therapeutic aspects of adrenoleukodystrophy and adrenomyeloneuropathy.
Journal of neuropathology and experimental neurology - 1 Sept 1995
Moser H W
Abstract excerpt
Adrenoleukodystrophy (ALD) and its adult variant adrenomyeloneuropathy (AMN) are X-linked diseases in which a deficiency of lignoceroyl-CoA ligase, a peroxisomal enzyme needed for the degradation of very long chain fatty acids (VLCFA), has been reported. The responsible gene recently has been clo...
Topics
- Adolescent
- Adrenoleukodystrophy
- Adult
- Bone Marrow Transplantation
- Child
- Dietary Fats, Unsaturated
- Drug Combinations
- Erucic Acids
- Family
- Frameshift Mutation
- Gene Deletion
- Humans
- Male
- Phenotype
- Triolein