Article
Both allelic forms of the rat T cell differentiation marker RT6 display nicotinamide adenine dinucleotide (NAD)-glycohydrolase activity, yet only RT6.2 is capable of automodification upon incubation with NAD.
European journal of immunology - 1 Aug 1995
Haag F, Andresen V, Karsten S, Koch-Nolte F, Thiele H
Abstract excerpt
The finding that recently cloned mono-ADP-ribosyltransferases show sequence similarity to the rat T cell differentiation marker RT6 has led us to investigate the enzymatic activity of this alloantigenic system. To search for ADP-ribosylation of cell surface proteins, T cell populations from RT6.1...
Topics
- ADP Ribose Transferases
- Alleles
- Animals
- Antigens, Differentiation, T-Lymphocyte
- Cells, Cultured
- Histocompatibility Antigens
- Lymph Nodes
- Membrane Glycoproteins
- NAD
- NAD+ Nucleosidase
- Poly(ADP-ribose) Polymerases