Article
Dystrophin-positive fibers in Duchenne dystrophy: origin and correlation to clinical course.
Muscle & nerve - 1 Oct 1995
Fanin M, Danieli G A, Cadaldini M, Miorin M, Vitiello L, Angelini C
Abstract excerpt
In 132 DMD muscle biopsies we investigated the presence of dystrophin-positive fibers and the relationship of dystrophin immunohistochemical pattern to the clinical severity of the disease. Reverted fibers were detected in 37% of patients; their prevalence increased significantly in each biopsy w...
Topics
- Biopsy
- Child
- Child, Preschool
- DNA, Complementary
- Dystrophin
- Humans
- Immunohistochemistry
- Models, Genetic
- Muscle Fibers, Skeletal
- Muscular Dystrophies
- Mutation
- Severity of Illness Index
- Time Factors