Article
[Resistance to its own antibiotic nigericin and macromolecular synthesis in Streptomyces hygroscopicus 155].
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] - 1 Apr 1995
Ivanova I V, Khristova K R, Moncheva P A, Miteva V I
Abstract excerpt
The influence of nigericin (nandavir) on the organism producing it (Streptomyces hygroscopicus 155) was studied with respect to the synthesis of protein, RNA and DNA. The resistance of the mycelium of different ages to the exogenic antibiotic was investigated. Exogenic nigericin had a more marked inhibitory effect on the macromolecular synthesis in a nonproductive variant of the strain. The antibiotic sensitivity...
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