Article
HLA -A, -B, -DR haplotype frequencies in France--implications for recruitment of potential bone marrow donors.
Transplantation - 27 Aug 1995
Lonjou C, Clayton J, Cambon-Thomsen A, Raffoux C
Abstract excerpt
We have undertaken a study of the haplotypes among French potential bone marrow donors in order to define the geographical regions of France with the maximum of polymorphism and also to develop a strategy for optimal donor recruitment. A maximum likelihood estimator was used to calculate haplotype frequencies and their support limits for each region and for the whole of France. The observed differences between...
Topics
- Alleles
- Bone Marrow Transplantation
- France
- Gene Frequency
- Geography
- HLA-A Antigens
- HLA-B Antigens
- HLA-DR Antigens
- Haplotypes
- Humans
- Tissue Donors
