Article
Effects of basic fibroblast growth factor on proliferation, the expression of osteonectin (SPARC) and alkaline phosphatase, and calcification in cultures of human pulp cells.
Developmental biology - 1 Aug 1995
Shiba H, Nakamura S, Shirakawa M, Nakanishi K, Okamoto H, Satakeda H, Noshiro M, Kamihagi K, Katayama M, Kato Y
Abstract excerpt
Basic fibroblast growth factor (bFGF) may be involved in the development and repair of dentine and pulp because bFGF, its related peptides, and FGF receptors are expressed in dental mesenchymal cells. In this study, we examined the effects of bFGF on DNA synthesis, osteonectin/SPARC levels, alkal...
Topics
- Alkaline Phosphatase
- Calcium
- Cell Division
- Cell Line
- DNA
- DNA, Complementary
- Dental Pulp
- Fibroblast Growth Factor 2
- Filaggrin Proteins
- Gene Expression
- Humans
- Odontoblasts
- Osteonectin
- Phenotype