Article
Extensive tissue oxygenation associated with mitochondrial DNA mutations.
Biochemical and biophysical research communications - 15 Aug 1995
Ozawa T, Sahashi K, Nakase Y, Chance B
Abstract excerpt
Extensive tissue oxygenation in the mitochondrial myopathy patients caused by the mitochondrial DNA mutations was first demonstrated noninvasively by a tissue oxymeter measuring near infrared light. The extent of oxygenation of the tissue due to dysfunction of mitochondria correlated with the ser...
Topics
- Adult
- Case-Control Studies
- DNA, Mitochondrial
- Exercise Test
- Female
- Gene Deletion
- Humans
- Male
- Mitochondrial Myopathies
- Mutation
- Ophthalmoplegia, Chronic Progressive External
- Oxidative Phosphorylation
- Oxidative Stress
- Oxygen Consumption
- Point Mutation
- RNA, Transfer, Tyr