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Article

Severe intrauterine growth retardation with increased mitomycin C sensitivity: a further chromosome breakage syndrome.

Journal of medical genetics - 1 Apr 1995

Woods C G, Leversha M, Rogers J G

Abstract excerpt

We report an infant with pre- and postnatal microcephaly and growth retardation, a distinctive face, and developmental delay. The initial diagnosis was of Seckel syndrome. He became pancytopenic at 16 months and died soon after. His bone marrow was of normal cellularity but had a small lymphocyte infiltration. Increased spontaneous chromosome breakage was seen in blood and fibroblasts. Mitomycin C induced...

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Identifiers

PMID: 7643362
DOI: 10.1136/jmg.32.4.301
PMCID: PMC1050381

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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