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Article

5-Fluoroindole resistance identifies tryptophan synthase beta subunit mutants in Arabidopsis thaliana.

Genetics - 1 May 1995

Barczak A J, Zhao J, Pruitt K D, Last R L

Abstract excerpt

A study of the biochemical genetics of the Arabidopsis thaliana tryptophan synthase beta subunit was initiated by characterization of mutants resistant to the inhibitor 5-fluoroindole. Thirteen recessive mutations were recovered that are allelic to trp2-1, a mutation in the more highly expressed of duplicate tryptophan synthase beta subunit genes (TSB1). Ten of these mutations (trp2-2 through trp2-11) cause a...

Topics

Alleles
Amino Acid Sequence
Arabidopsis
Base Sequence
Drug Resistance
Genes, Plant
Indoles
Molecular Sequence Data
Mutagenesis
Plant Proteins
Tryptophan Synthase

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Identifiers

PMID: 7635295
DOI: 10.1093/genetics/140.1.303
PMCID: PMC1206557

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7635295-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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