Complement component C6 and C7 haplotypes associated with deficiencies of C6.

doi:10.1111/j.1469-1809.1995.tb00740.x

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Article

Complement component C6 and C7 haplotypes associated with deficiencies of C6.

Annals of human genetics - 1 Apr 1995

Fernie B A, Orren A, Würzner R, Jones A M, Potter P C, Lachmann P J, Hobart M J

Abstract excerpt

Both complete C6-deficiency (C6*Q0) and subtotal C6-deficiency (C6*SD) have been described as simple recessive traits and C6*SD has been described in combination with subtotal deficiency of the C7 coded at an adjacent locus. The trace of C6 protein found in both C6*SD traits is phenotypically ind...

Topics

Alleles
Complement C6
Complement C7
Female
Genetic Markers
Genotype
Haplotypes
Humans
Male
Pedigree
Phenotype
Polymorphism, Restriction Fragment Length

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