Article
Localization of genes for two members of the JAK family of protein tyrosine kinases to murine chromosomes 4 and 19.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Apr 1995
Gough N M, Rakar S, Harpur A, Wilks A F
Abstract excerpt
Genes encoding two members of the JAK family of protein tyrosine kinases, Jak-1 and Jak-2, have been mapped to mouse Chromosomes (Chrs) 4 and 19 respectively. These placements are consistent with the previously described location of human JAK1 and JAK2, which lie in regions of synteny on human Chrs 1p31-3 (JAK1) and 9p24 (JAK2). The location of Jak-2 in the mouse genome extends the region of homology between...
Topics
- Alleles
- Animals
- Chromosome Mapping
- Chromosomes
- Genetic Linkage
- Janus Kinase 1
- Janus Kinase 2
- Mice
- Mice, Inbred Strains
- Polymorphism, Restriction Fragment Length
- Protein-Tyrosine Kinases
