Genetic mapping of the gene for a novel tyrosine kinase, Blk, to mouse chromosome 14.

doi:10.1016/0888-7543(91)90372-l

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Article

Genetic mapping of the gene for a novel tyrosine kinase, Blk, to mouse chromosome 14.

Genomics - 1 Apr 1991

Kozak C A, Dymecki S M, Niederhuber J E, Desiderio S V

Abstract excerpt

The gene Blk, which encodes a novel tyrosine kinase expressed preferentially in B-lymphoid cells, was mapped by Southern blot analysis of DNA from the progeny of an intersubspecific backcross. Blk maps to the proximal region of chromosome 14 with the gene order centromere--(Np-1,Tcra)-Blk-sys-Es-10.

Topics

Alleles
Animals
B-Lymphocytes
Blotting, Southern
Chromosome Mapping
Crosses, Genetic
Mice
Protein-Tyrosine Kinases

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