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Article

Refractory hypertension is associated with the haptoglobin 2-2 phenotype.

Journal of cardiovascular risk - 1 Apr 1995

Delanghe J R, Duprez D A, De Buyzere M L, Bergez B M, Claeys L R, Leroux-Roels G G, Clement D L

Abstract excerpt

BACKGROUND: Many cases of refractory hypertension cannot be attributed to specific identifiable factors. Haptoglobin polymorphism has been suggested as a candidate genetic marker in essential hypertension. The aim of this study was to investigate the distribution of haptoglobin types in patients with refractory hypertension. METHODS: Haptoglobin polymorphism was studied in 383 patients with non-refractory and 62...

Topics

Alleles
Antihypertensive Agents
Blood Pressure
Drug Combinations
Female
Gene Frequency
Genetic Markers
Haptoglobins
Humans
Hypertension
Hypertrophy, Left Ventricular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Phenotype

Polymorphism, Genetic

Source

Identifiers

PMID: 7606649

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7606649-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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