Article
Role of major histocompatibility complex class I expression and natural killer-like T cells in the genetic control of endometriosis.
Fertility and sterility - 1 Nov 1995
Semino C, Semino A, Pietra G, Mingari M C, Barocci S, Venturini P L, Ragni N, Melioli G
Abstract excerpt
OBJECTIVE: To evaluate whether the expression of human leukocyte antigen (HLA) class I on eutopic and ectopic endometrial cells modify the susceptibility to lysis mediated by lymphocytes. DESIGN: Evaluation of T lymphocyte cytotoxic activity and HLA class I expression on endometrial cells. SETTING: Subjects were recruited at laparoscopy. PATIENTS: Patients with endometriosis (n = 7). Healthy women as controls (n...
Topics
- Alleles
- Cells, Cultured
- Down-Regulation
- Endometriosis
- Endometrium
- Female
- Flow Cytometry
- Fluorescent Antibody Technique, Indirect
- Gene Expression Regulation
- Genes, MHC Class I
