Article
Factor V Leiden and risks of recurrent idiopathic venous thromboembolism.
Circulation - 15 Nov 1995
Ridker P M, Miletich J P, Stampfer M J, Goldhaber S Z, Lindpaintner K, Hennekens C H
Abstract excerpt
BACKGROUND: Whether Leiden mutation in the gene coding for coagulation factor V is associated with recurrent idiopathic venous thromboembolism (VTE) is unknown, but such data are necessary to evaluate the merits of genetic screening in secondary prevention of thromboembolic disease. METHODS AND RESULTS: Among 14,916 apparently healthy men who provided DNA samples and were followed in the Physicians' Health Study...
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