Article
Analysis of a repeat-containing family of Giardia lamblia variant-specific surface protein genes: diversity through gene duplication and divergence.
The Journal of eukaryotic microbiology - 1 Jan 2000
Yang Y M, Adam R D
Abstract excerpt
Giardia lamblia trophozoites express on their surfaces one of a set of cysteine-rich antigenically variant proteins, called variant-specific surface proteins, which comprise the majority of proteins detected by surface labeling. While these VSP proteins may be immunodominant proteins important in the host immune response to G. lamblia, the ability to switch expression from one VSP to another may provide a means...
Topics
- Amino Acid Sequence
- Animals
- Antibodies, Protozoan
- Antigens, Protozoan
- Antigens, Surface
- Base Sequence
- Cloning, Molecular
- DNA, Protozoan
- Genes, Protozoan
- Genetic Variation
- Giardia lamblia