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Article

Overexpression of DM20 messenger RNA in two brothers with Pelizaeus-Merzbacher disease.

Annals of neurology - 1 Oct 1995

Carango P, Funanage V L, Quirós R E, Debruyn C S, Marks H G

Abstract excerpt

Pelizaeus-Merzbacher disease is a rare, sex-linked recessive, dysmyelinating disease of the central nervous system that has been associated with mutations in the myelin proteolipid protein (PLP) gene. Only 25% of patients studied with Pelizaeus-Merzbacher disease have exonic mutations in this gene, the underlying cause of the disease in the remaining patients is unknown. The PLP gene encodes two major...

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PMID: 7574457
DOI: 10.1002/ana.410380409

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Overexpression of DM20 messenger RNA in two brothers with Pelizaeus-Merzbacher disease.PMID 7574457Read ↗

A novel insertional mutation at exon VII of the myelin proteolipid protein gene in Pelizaeus-Merzbacher disease.Semantic proximity Read ↗

The proteolipid protein gene and myelin disorders in man and animal models.Semantic proximity Read ↗

A missense mutation in the proteolipid protein gene responsible for Pelizaeus-Merzbacher disease in a Japanese family.Semantic proximity Read ↗

Mutations in noncoding regions of the proteolipid protein gene in Pelizaeus–Merzbacher diseaseSemantic proximity Read ↗

Pelizaeus-Merzbacher disease: a valine to phenylalanine point mutation in a putative extracellular loop of myelin proteolipid.Semantic proximity Read ↗

A case of Pelizaeus-Merzbacher disease showing increased dosage of the proteolipid protein gene.Semantic proximity Read ↗

Two autopsy cases with Pelizaeus-Merzbacher disease phenotype of adult onset, without mutation of proteolipid protein gene.Semantic proximity Read ↗

Pelizaeus-Merzbacher disease: a novel mutation in the 5'-untranslated region of the proteolipid protein gene.Semantic proximity Read ↗

Proteolipid protein gene duplications causing Pelizaeus-Merzbacher disease: molecular mechanism and phenotypic manifestations.Semantic proximity Read ↗

Schwann cell expression of PLP1 but not DM20 is necessary to prevent neuropathy.Semantic proximity Read ↗

Mutations in the proteolipid protein gene in Japanese families with Pelizaeus-Merzbacher disease.Semantic proximity Read ↗

Peripheral neuropathy caused by proteolipid protein gene mutations.Semantic proximity Read ↗

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