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Article

Ala 586 Asp mutation in androgen receptor disrupts transactivation function without affecting androgen binding.

Fertility and sterility - 1 Mar 2009

Rajender Singh, Gupta Nalini J, Chakrabarty Baidyanath, Singh Lalji, Thangaraj Kumarasamy

Abstract excerpt

OBJECTIVE: To understand the pathogenesis of the androgen insensitivity syndrome. DESIGN: Familial case study. SETTING: Medical and Evolutionary Genetics Laboratory, Centre for Cellular and Molecular Biology, Hyderabad, India. PATIENT(S): Two affected sisters and other unaffected family members. INTERVENTION(S): The hormone levels were measured by RIA. Histology was done by standard protocols. DNA isolation and...

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Identifiers

PMID: 19062009
DOI: 10.1016/j.fertnstert.2008.10.041

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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