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Article

Fluorescent multiplex microsatellites used to identify haplotype associations with 15 CFTR mutations in 124 Northern Irish CF families.

Human genetics - 1 Apr 1995

Hughes D, Hill A, Redmond A, Nevin N, Graham C

Abstract excerpt

The cystic fibrosis transmembrane conductance regulator gene contains three highly informative microsatellites; IVS8CA, IVS17BTA and IVS17BCA. Fluorescent multiplexes of these microsatellites were assayed in 124 CF families carrying 15 different CFTR mutations, from N. Ireland.

Topics

Child, Preschool
Cystic Fibrosis
Cystic Fibrosis Transmembrane Conductance Regulator
DNA, Satellite
Fluorescent Dyes
Gene Frequency
Haplotypes
Humans
Ireland
Membrane Proteins
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 7535745
DOI: 10.1007/BF00208979

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7535745-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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