Article
Genetic and clinical mosaicism in a type of epidermal nevus.
The New England journal of medicine - 24 Nov 1994
Paller A S, Syder A J, Chan Y M, Yu Q C, Hutton E, Tadini G, Fuchs E
Abstract excerpt
BACKGROUND: Many skin disorders are characterized by a mosaic pattern, often with alternating stripes of affected and unaffected skin that follow the lines of Blaschko. These nonrandom patterns may be caused by a postzygotic mutation during embryogenesis. We studied the genetic basis of one such disorder, epidermal nevus of the epidermolytic hyperkeratotic type. Epidermolytic hyperkeratosis is an autosomal...
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