Mosaicism in human skin. Understanding the patterns and mechanisms.

Abstract excerpt

BACKGROUND: The skin is especially suitable for the study of mosaicism. In this review, the various genetic mechanisms leading to mosaicism and the resulting cutaneous patterns are considered. OBSERVATIONS: Mosaicism may produce different cutaneous patterns such as the lines of Blaschko, the checkerboard pattern, the phylloid pattern, and a patchy pattern without midline separation. A unique lateralization...

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