CFTR haplotype backgrounds on normal and mutant CFTR genes.

doi:10.1093/hmg/3.4.607

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Article

CFTR haplotype backgrounds on normal and mutant CFTR genes.

Human molecular genetics - 1 Apr 1994

Cuppens H, Teng H, Raeymaekers P, De Boeck C, Cassiman J J

Abstract excerpt

Ten polymorphic loci, located in a 1 Mb interval across the cystic fibrosis locus, were analyzed on normal and mutant CFTR genes. A different distribution of haplotype backgrounds among normal and mutant CFTR genes was observed. With exception of the D7S8 locus, the three most common mutations, d...

Topics

Alleles
Base Sequence
Cystic Fibrosis
Cystic Fibrosis Transmembrane Conductance Regulator
Gene Deletion
Genes
Haplotypes
Humans
Linkage Disequilibrium
Membrane Proteins
Molecular Sequence Data
Mutation
Polymorphism, Genetic
Selection, Genetic

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