Article
Expression of phenotypic markers during regeneration of rat tracheal epithelium following mechanical injury.
American journal of respiratory cell and molecular biology - 1 Jul 1994
Shimizu T, Nishihara M, Kawaguchi S, Sakakura Y
Abstract excerpt
We examined epithelial regeneration in mechanically injured rat trachea using phenotypic markers that identify unique differentiated stages of epithelial cells. Following a focal denuding wound, the cells from the adjacent nonwounded epithelium flattened and migrated into the wounded site during the first 12 h. At 24 h, these cells dedifferentiated into poorly differentiated (PD) cells that did not precisely...
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