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Article

Functional studies of the carboxy-terminal repeat domain of Drosophila RNA polymerase II in vivo.

Genetics - 1 Jun 1995

Brickey W J, Greenleaf A L

Abstract excerpt

To understand the in vivo function of the unique and conserved carboxy-terminal repeat domain (CTD) of RNA polymerase II largest subunit (RpII215), we have studied RNA polymerase II biosynthesis, activity and genetic function in Drosophila RpII215 mutants that possessed all (C4), half (W81) or none (IIt) of the CTD repeats. We have discovered that steady-state mRNA levels from transgenes encoding a fully...

Topics

Animals
Animals, Genetically Modified
Blotting, Northern
Blotting, Southern
DNA
Drosophila melanogaster
Genetic Complementation Test
Mutation
RNA Polymerase II
RNA, Messenger
Repetitive Sequences, Nucleic Acid

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Identifiers

PMID: 7498740
DOI: 10.1093/genetics/140.2.599
PMCID: PMC1206638

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7498740-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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