Article
Gradient of genomic diversity in the Pseudomonas aeruginosa chromosome.
Molecular microbiology - 1 Jul 1995
Römling U, Greipel J, Tümmler B
Abstract excerpt
In 545 Pseudomonas aeruginosa strains, mainly collected from patients with cystic fibrosis, SpeI-DraI macrorestriction fragment length diversity was scanned for using probes of known map position on the P. aeruginosa PAO chromosome. Southern analysis of the 60 unrelated clones uncovered a gradient of macrorestriction fragment length polymorphisms (RFLPs) from the origin of replication towards the auxotroph-poor...
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