Article
The adenovirus protease is required for virus entry into host cells.
Virology - 10 Nov 1995
Cotten M, Weber J M
Abstract excerpt
We have analyzed the mechanisms used by adenovirus to gain entry into the host cell. Using both virus infection and the ability of adenovirus particles to enhance polylysine/DNA uptake as a measure of virus entry, we have demonstrated that the adenovirus-encoded 23K protease is required for two functions in the infection process. A proteolytic processing of the capsid is required to generate a virus capsid that...
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