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Article

Mutations in conserved domain I of the Sendai virus L polymerase protein uncouple transcription and replication.

Virology - 10 Nov 1995

Chandrika R, Horikami S M, Smallwood S, Moyer S A

Abstract excerpt

To begin to map functional domains of the Sendai P-L RNA polymerase complex we wanted to characterize the P binding site on the Sendai L protein. Analysis of in vitro and in vivo P-L polymerase complex formation with carboxyl-truncations of the L protein showed that the N-terminal half of the protein was required. Site-directed mutagenesis of the Sendai virus L gene was employed to change amino acids within a...

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PMID: 7491760
DOI: 10.1006/viro.1995.0008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Mutations in conserved domain I of the Sendai virus L polymerase protein uncouple transcription and replication.PMID 7491760Read ↗

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