Article
Reconstructing the complex evolutionary history of hepatitis B virus.
Journal of molecular evolution - 1 Jul 1999
Bollyky P L, Holmes E C
Abstract excerpt
A detailed analysis of the evolutionary history of hepatitis B virus (HBV) was undertaken using 39 mammalian hepadnaviruses for which complete genome sequences were available, including representatives of all six human genotypes, as well as a large sample of small S gene sequences. Phylogenetic trees of these data were ambiguous, supporting no single place of origin for HBV, and depended heavily on the underlying...
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