Article
Protein S mRNA in patients with protein S deficiency.
Thrombosis and haemostasis - 1 May 1995
Sacchi E, Pinotti M, Marchetti G, Merati G, Tagliabue L, Mannucci P M, Bernardi F
Abstract excerpt
A protein S gene polymorphism, detectable by restriction analysis (BstXI) of amplified exonic sequences (exon 15), was studied in seven Italian families with protein S deficiency. In the 17 individuals heterozygous for the polymorphism the study was extended to platelet mRNA through reverse trans...
Topics
- Alleles
- Base Sequence
- Blood Platelets
- Deoxyribonucleases, Type II Site-Specific
- Female
- Genotype
- Humans
- Male
- Molecular Sequence Data
- Pedigree
- Phenotype
- Polymorphism, Restriction Fragment Length
- Protein S
- Protein S Deficiency
- RNA, Messenger